Job’s Syndrome With a Family History of Kawasaki Disease: A Case Presentation and Review of Literature

Background: Job’s syndrome or hyper-immunoglobulin E (IgE) (HIES) is an extremely rare primary immunodeficiency disease with approximate annual incidence of less than 1/1000000. It characterized by recurrent cold staphylococcal infections, unusual eczematous dermatitis, severe lung and extensively high concentrations the serum antibody IgE. Case Presentation: A typical case a family history Kawasaki presented in this study aiming at identifying clinical features, investigational procedures, management strategy, as well evaluating role ear, nose, throat specialist highlighting probable relation between disease. Conclusions: In general, early detection proper care can prevent progression Job syndrome. addition, initiated treatment first signs infection mandatory for preventing long-term complications. There which requires more consideration.